In this article I study Kant's doctrine of the power of judgement. I focus on its main function of rendering possible the transition from the lawfulness of nature to the realization of practical ends. In order to do so, I analyze the concept of “spontaneity” and the principle of “purposiveness of nature”, understood as a “principle of contingency”, according to Kant's explanation in the Critique of the Power of Judgement.

La expansión de las actividades informales de feriantes en el conurbano bonaerense constituye una de las manifestaciones del fenómeno de la heterogeneidad no regulada del aprovisionamiento de bienes de consumo, que a su vez, emergen como intermediarios económicos que atienden a necesidades y demandas de consumidores territorialmente segregados y no articulados a los mercados formales, en su mayoría.Es en ese sentido que el presente artículo quiere rescatar y señalar los componentes centrales que asoman en un proceso que parte con el (...) supuesto de que la confianza constituye un elemento central cuando otras formas que actuarían como garante de las interacciones aparecen débiles, ausentes o no primordiales como garantía de las interacciones sociales, como es el caso de la feria de Solano. (shrink)

Al final de la Crítica de la facultad de juzgar, Kant aborda el problema de las pruebas de la existencia de Dios y revisa en detalle el argumento que a él le parece el único capaz de provocar verdadero asentimiento: la prueba moral. Se revisa el camino que sigue Kant para llegar, a través de su anál..

Uno de los problemas que se le presentan a Kant en la Crítica de la facultad de juzgar es el de la aptitud de la naturaleza en su diversidad particular para ser conformada por las leyes del entendimiento. En este contexto, Kant defi ne los conceptos de naturaleza, materia y fi nalidad de una manera que antes no había tenido cabida en su sistema, y postula la idea de una técnica o arte de la naturaleza. En este artículo se analiza (...) y discute cómo Kant aborda esto, haciendo hincapié en el papel que juega el principio de la conformidad a fi n en el marco de una naciente ciencia de los seres vivos.One of the problems for Kant in the Critique of Judgment is the suitability of nature's particular diversity to the laws of the understanding. In this context, Kant characterizes the concepts of nature, matter and purposiveness in a novel fashion, putting forward the idea of an art or technique of nature. This article considers this new Kantian approach emphasizing the role played by the principle of purposiveness in a context in which a new science of living beings is emerging. (shrink)

En este trabajo se intenta mostrar en primer lugar que la noción de providencia que Kant presenta en obras como Sobre la paz perpetua e Idea para una historia universal en clave cosmopolita corresponde en algunos puntos centrales a la idea estoica de providencia; segundo, que es en este contexto donde puede evaluarse correctamente la noción kantiana de cosmopolitismo; y, por último, que este modo de enfrentar filosóficamente los problemas de la historia y la política responde a una exigencia de (...) sistematicidad exigida por la propia razón, según Kant, y que esta misma idea de sistema se conecta en buena medida con la filosofía de los estoicos. (shrink)

The pandemic has exposed the costs of job and income losses. Emergency cash transfers can mitigate the worst immediate effects on people who lack access to safety nets. This research note provides estimates for a potential Temporary Basic Income for poor and near-poor people across 132 developing countries, as well as the minimum cost of income support sufficient to mitigate the pandemic-induced poverty increase. The total monthly cost of the TBI ranges 0.27–0.63% of developing countries’ combined GDP, depending on the (...) choice: top-ups on each country’s average incomes up to a vulnerability threshold; transfers based on each country’s median standard of living; or uniform transfers. This note argues that some form of TBI is within reach and can inform a larger conversation about how to build comprehensive social protection systems that make the poor and near-poor more resilient to economic downturns in the future. (shrink)

Neste artigo, realiza-se uma discussão sobre as atividades políticas de María de Molina, regente do trono castelhano após a morte do esposo e rei Sancho IV, em 1295, durante a minoridade do filho Fernando IV, de 1295 a 1301, assim como no decurso da minoridade do neto Alfonso XI, de 1212 a 1325. Nesses quase vinte e seis anos na condução política do reino, María de Molina constitui-se o principal baluarte da resistência e das negociações dos assuntos do (...) reino diante dos interesses das principiais facções nobiliárias, que aproveitavam períodos de debilidade do poder régio para obter relevância política e dividendos. Não menos importante foi seu desempenho em relação à política externa ao celebrar diversos acordos com outros reinos e com o papado no desígnio de alcançar apoio para sequência da sua linhagem ao comando da coroa castelhana. (shrink)

The main idea that we want to defend in this paper is that the question of what a logic is should be addressed differently when structural properties enter the game. In particular, we want to support the idea according to which it is not enough to identify the set of valid inferences to characterize a logic. In other words, we will argue that two logical theories could identify the same set of validities, but not be the same logic.

The facultative intracellular pathogen Salmonella enterica serovar Typhimurium faces multiple environments during infection, including different cell types as well as extracellular fluids. We propose that Salmonella ascertains its cellular location by assessing the Mg2+ concentration of its milieu. A signal transduction system, PhoP/PhoQ, signals Salmonella its presence in a intracellular (low Mg2+) or extracellular (high Mg2+) environment, thereby promoting transcription of genes required for survival within or entry into host cells. The PhoP/PhoQ system is high in a regulatory hierarchy that (...) controls other signal transduction systems that respond to different host cues, enabling the microorganism to determine its precise tissue and cellular location. BioEssays 20:96–101, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

From a scientific standpoint, the world is more prepared than ever to respond to infectious disease outbreaks; paradoxically, globalization and air travel, antimicrobial resistance, the threat of bioterrorism, and newly emerging pathogens driven by ecological, socioeconomic, and environmental factors, have increased the risk of global epidemics.1,2,3 Following the 2002–2003 severe acute respiratory syndrome (SARS), global efforts to build global emergency response capabilities to contain infectious disease outbreaks were put in place.4,5,6 But the recent H1N1, Ebola, and Zika global epidemics have (...) shown unnecessary delays and insufficient coordination in response efforts.7,8,9,10 In a thoughtful and compelling essay,11 Thana C. de Campos argues that greater clarity in the definition of pandemics would probably result in more timely effective emergency responses, and pandemic preparedness. In her view, a central problem is that the definition of pandemics is based solely on disease transmission across several countries, and not on spread and severity together, which conflates two very different situations: emergency and nonemergency disease outbreaks. A greater emphasis on severity, such that pandemics are defined as severe and rapidly spreading infectious disease outbreaks, would make them “true global health emergencies,” allowing for priority resource allocation and effective collective actions in emergency response efforts. Sympathetic to the position taken by de Campos, here I highlight some of the challenges in the definition of severity during an infectious disease outbreak. (shrink)

What accounts for the apocalyptic angst that is now so clearly present among Americans who do not subscribe to any religious orthodoxy? Why do so many popular television shows, films, and music nourish themselves on this very angst? And why do so many artists—from Coldplay to Tori Amos to Tom Wolfe—feel compelled to give it expression? It is tempting to say that America’s fears and anxieties are understandable in the light of 9/11, the ongoing War on Terror, nuclear proliferation, and (...) the seemingly limitless capacity of science to continually challenge our conceptions of the universe and ourselves. Perhaps, too, American culture remains so permeated by Protestant Christianity that even avowed skeptics cannot pry themselves from its grip. In _A Consumer’s Guide to the Apocalypse,_ Eduardo Velásquez argues that these answers are too pat. Velásquez’s astonishing thesis is that when we peer into contemporary artists’ creative depiction of our sensibilities we discover that the antagonisms that fuel the current cultural wars stem from the same source. Enthusiastic religions and dogmatic science, the flourishing of scientific reason and the fascination with mystical darkness, cultural triumphalists and multicultural ideologues are all sustained by the same thing: a willful commitment to the basic tenets of the Enlightenment. Velásquez makes his point with insightful readings of the music of Coldplay, Tori Amos, and Dave Matthews and the fiction of Michael Frayn’s _Copenhagen,_ Chuck Palahniuk’s _Fight Club,_ and Tom Wolfe’s _I Am Charlotte Simmons._ Written with grace and humor, and directed toward the lay reader, _A Consumer’s Guide to the Apocalypse_ is a tour de force of cultural analysis. (shrink)

The origins and development of the problem of mental causation are outlined. The underlying presuppositions which give rise to the problem are identified. Possible strategies for solving, or dissolving the problem are examined.

Horizontal gene transfer advances bacterial evolution. To benefit from horizontally acquired genes, enteric bacteria must overcome silencing caused when the widespread heat‐stable nucleoid structuring (H‐NS) protein binds to AT‐rich horizontally acquired genes. This ability had previously been ascribed to both anti‐silencing proteins outcompeting H‐NS for binding to AT‐rich DNA and RNA polymerase initiating transcription from alternative promoters. However, we now know that pathogenic Salmonella enterica serovar Typhimurium and commensal Escherichia coli break down H‐NS when this silencer is not bound to (...) DNA. Curiously, both species use the same protease – Lon – to destroy H‐NS in distinct environments. Anti‐silencing proteins promote the expression of horizontally acquired genes without binding to them by displacing H‐NS from AT‐rich DNA, thus leaving H‐NS susceptible to proteolysis and decreasing H‐NS amounts overall. Conserved amino acid sequences in the Lon protease and H‐NS cleavage site suggest that diverse bacteria degrade H‐NS to exploit horizontally acquired genes. (shrink)

In his article “The Status of Content”, Boghossian defends what has been called “trascendentalism about content”. According to him, the thesis that there is nothing in the world that corresponds to our thoughts “is not merely implausible but incoherent”. In other words, he thinks that the thesis in question is not simply false on empirical basis but rather self-refuting or pragmatically incoherent. My purpose in this article is to show that Boghossian´s argument for his point of view is not valid. (...) My main thesis is that there is no contradiction in applying the notion of truth to both semantical and psychological sentences and, at the same time, holding that there are neither semantic nor mental contents. (shrink)

Esta sección temática constituye la segunda discusión sobre el desafío de la adopción de reglas lógicas publicado en Análisis Filosófico. Al igual que la primera, esta colección de artículos puede verse como el resultado de la colaboración internacional que durante más de dos décadas hemos mantenido entre el Saul Kripke Center (SKC) y el IIF-SADAF-CONICET. Y más precisamente, entre Saul, Romina y el grupo de lógica de Buenos Aires (BA-Logic). Visitas, seminarios, workshops, proyectos internacionales, y fundamentalmente mucho afecto y pasión (...) por los problemas filosóficos fundamentales han marcado este proceso. Tanto Romina como Saul han apoyado sistemáticamente los esfuerzos desde Argentina para producir conocimiento en el área de lógica. Ambos han estado involucrados no solo institucionalmente en el apoyo al desarrollo de nuestro grupo, sino también a nivel personal. Fueron muchos los momentos que compartimos juntos. Muchos recuerdos e historias. Es importante destacar, solo para mencionar un simple aspecto de nuestras historias comunes, que Saul participó activamente en el proceso de elaboración de la propuesta de ambos números, en la lectura de gran parte del material, e incluso como réferi de algunos trabajos. Saul y Romina asistieron por Zoom a varias reuniones en el marco de los seminarios que generaron parte del material aquí publicado. Recuerdo la alegría de Saul, sus comentarios y la sorpresa de muchos de los participantes de ver aparecer en sus pantallas al filósofo más importante del mundo y uno de los más importantes de la historia. Para ellos quizás era Kripke, para mi ya era Saul. Nos hubiera gustado celebrar juntos. Podría haber sido en Buenos Aires o en Nueva York. Lamentablemente, ya no podrá ser. Aunque también es cierto que esta sección temática es una manera de volver a reunirnos y de expresar el profundo agradecimiento que todos los integrantes del BA-Logic tenemos por Saul. Te vamos a extrañar… Ya te estamos extrañando…. (shrink)

The global economy’s centre of gravity is shifting. Emerging and developing countries have been contributing over 50% of the global GDP since the onset of the 21st century, which is unprecedented since the Industrial Revolution. This article offers the first analysis of the creeping convergence of the BRIC world (ie Brazil, Russia, India and China) with global legal standards in a key area of International Law: the International Tax Regime (ITR). The ITR is a legal technology fundamentally designed by the (...) League of Nations in the 1920s, when the BRICs played no relevant role. This article proposes a theory that aims to illuminate the core driving forces of the on-going trend towards global convergence in this area of International Law from both the static and dynamic dimensions. It is grounded on the logic of two-sided platforms. (shrink)

Music reduces pain in fibromyalgia (FM), a chronic pain disease, but the functional neural correlates of music-induced analgesia (MIA) are still largely unknown. We recruited FM patients ( n = 22) who listened to their preferred relaxing music and an auditory control (pink noise) for 5 min without external noise from fMRI image acquisition. Resting state fMRI was then acquired before and after the music and control conditions. A significant increase in the amplitude of low frequency fluctuations of the BOLD (...) signal was evident in the left angular gyrus (lAnG) after listening to music, which in turn, correlated to the analgesia reports. The post-hoc seed-based functional connectivity analysis of the lAnG showed found higher connectivity after listening to music with right dorsolateral prefrontal cortex (rdlPFC), the left caudate (lCau), and decreased connectivity with right anterior cingulate cortex (rACC), right supplementary motor area (rSMA), precuneus and right precentral gyrus (rPreG). Pain intensity (PI) analgesia was correlated ( r = 0.61) to the connectivity of the lAnG with the rPreG. Our results show that MIA in FM is related to top-down regulation of the pain modulatory network by the default mode network (DMN). (shrink)

El objetivo de este artículo es evaluar la importancia de los líderes africanos en la política exterior de sus países. A partir de una revisión comprehensiva de literatura especializada, se evidencia la intrascendencia en África de los marcos teóricos tradicionales del análisis de política exterior, los cuales se basan principalmente en la experiencia diplomática de las grandes potencias. En el contexto de los países africanos, por el contrario, la unidad decisoria final no está institucionalizada, por lo cual la visión de (...) mundo de los líderes se transforma en prácticamente la única referencia para la fijación de la estrategia internacional y el interés nacional. (shrink)

In this article I analyze the class- and cultural-based exclusion produced by the Chilean neoliberal educational reform, carried out during the period from 1990 to 2010. This educational reform follows the same neoliberal model applied to the economy of the country. Although some indicators improved in relation to coverage and public spending in education, the performance gap among social groups increased. In addition, at a cultural level, the reform promoted the value of individual productivity negatively affecting some of the cultural (...) behaviors developed by low-income groups as a consequence of and as reaction to the exclusion they suffer. Namely, by stressing the notions of human capital and quality education, the reform has tended to reinforce these students? fatalism, and limit the scope of the organizations they form to improve their academic and social opportunities. (shrink)

In this paper I criticize Comesaña's point of view on Putnam's model-theoretic argument. I claim that there is an interesting point made by the argument that Comesaña has not taken into account: if we want our semantic assertions to be at ali justified, the externalist claim according to which justification requires the God 's Eye View has to be given up.

Nowadays global inequalities in access to vaccines seem to be a growing problem. Intellectual Property Rights have been playing an important role both in causing and worsening them. Firstly,...

¿Podemos adoptar una regla de inferencia como si fuera una hipótesis e inferir algo en virtud de esa regla? ¿Podemos revisar nuestras reglas y principios lógicos en virtud de la evidencia disponible? El antiexcepcionalismo lógico desafía la idea de que la lógica es excepcional y la vincula con el resto de las teorías científicas. Sin embargo, el desafío de la adopción planteado por Kripke y Padró imponen límites a esta concepción. En esta sección, se exploran distintos aspectos vinculados a la (...) imposibilidad de adoptar reglas, el antiexcepcionalismo, la revisión y la normatividad de la lógica. (shrink)

¿Seguimos reglas de inferencia al razonar? Por más intuitiva que resulte la respuesta positiva a esta pregunta, hay una serie de dificultades para vincular reglas lógicas y prácticas inferenciales. El Problema de la Adopción de Reglas de Inferencia constituye un desafío para todo aquel que proponga que podemos seguir nuevos patrones inferenciales a partir del reconocimiento de reglas. En esta sección temática se exploran diversos asuntos conectados a si podemos seguir un nuevo patrón inferencial en virtud de una regla.

Feedback loops have been identified in a variety of regulatory systems and organisms. While feedback loops of the same type (negative or positive) tend to have properties in common, they can play distinctively diverse roles in different regulatory systems, where they can affect virulence in a pathogenic bacterium, maturation patterns of vertebrate oocytes and transitions through cell cycle phases in eukaryotic cells. This review focuses on the properties and functions of positive feedback in biological systems, including bistability, hysteresis and activation (...) surges. BioEssays 30:542–555, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

This paper examines ethics in organizations in relation to the subjectivity of managers. Drawing on the work of Michel Foucault we seek to theorize ethics in terms of the meaning of being a manager who is an active ethical subject. Such a manager is so in relation to the organizational structures and norms that govern the conduct of ethics. Our approach locates ethics in the relation between individual morality and organizationally prescribed principles assumed to guide personal action. In this way (...) we see ethics as a practice that is powerfully intertwined in an individual’s freedom to make choices about what to do and who to be, and the organizational context in which those choices are situated, framed and governed. (shrink)

This paper characterizes José Celestino Mutis’ appropriation of Newton in the Viceroyalty of New Granada. First, we examine critically traditional accounts of Mutis’ works highlighting, on the one hand, their inadequacy for directing their claims toward the nineteenth-century independence from Spain and, on the other, for not differentiating between Newtonianism and Enlightenment. Next, we portray Mutis’ complex Newtonianism from his own statements and from printed sources, including a variety of works and translations from British, Dutch, and French authors, in addition (...) to a wide range of Newton’s writings, unusual for an eighteenth-century reader in the Americas. Finally, we analyze a salient claim of Mutis’ Newtonianism in order to depict his appropriation and transformation of Newton’s ideas: the characterization of Newtonian experimental physics as a useful science. In so doing, Mutis further developed metaphysical and methodological positions not present in Newton’s works. (shrink)

En la primera parte del artículo se propone un análisis de la insuficiencia constitucional del ser humano en el contexto de la filosofía griega. Se presenta una crítica al concepto de autarquía y se analiza el carácter contracultural de los movimientos filosóficos del cinismo, estoicismo y epicureísmo. La negación relativa y absoluta de la alteridad son igualmente analizadas. En la segunda parte, se analiza la insuficiencia constitucional desde el concepto de pobreza en el contexto de la orden franciscana y su (...) renuncia a la propiedad. También se hace referencia a los argumentos de los teólogos de la escuela de Salamanca y finalmente se plantea en qué medida el discurso franciscano está presente hoy como discurso político revolucionario. El objetivo general de las dos partes es presentar dos momentos anómalos de nuestra historia filosófica y su posible carácter contracultural válido para una crítica al capitalismo actual. (shrink)

The claim according to which there is a categorial gap between meaning and saying ¿ between what sentences mean and what we say by using them on particular occasions ¿ has come to be widely regarded as being exclusively a claim in the philosophy of language. The present essay collection takes a different approach to these issues. It seeks to explore the ways in which that claim ¿ as defended first by ordinary language philosophy and, more recently, by various contextualist (...) projects ¿ is grounded in considerations that transcend the philosophy of language. More specifically, the volume seeks to explore how that claim is inextricably linked to considerations about the nature of truth and representation. It is thus part of the objective of this volume to rethink the current way of framing the debates on these issues. By framing the debate in terms of an opposition between "ideal language theorists" and their semanticist heirs on the one hand and "communication theorists" and their contextualist heirs on the other, one brackets important controversies and risks obscuring the undoubtedly very real oppositions that exist between different currents of thought. (shrink)